Medulloblastoma Clinical Trials

Phase I Study of APX005M in Pediatric CNS Tumors
Last Updated: 2020-02-20
Originally Posted: 2017-12-15

Volitinib in Treating Participants With Recurrent or Refractory Primary CNS Tumors
Last Updated: 2020-02-20
Originally Posted: 2018-07-24

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
Last Updated: 2020-02-20
Originally Posted: 2018-10-05

Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors
Last Updated: 2020-02-20
Originally Posted: 2018-10-09

PI3K/mTOR Inhibitor LY3023414 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)
Last Updated: 2020-02-19
Originally Posted: 2017-07-10

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)
Last Updated: 2020-02-19
Originally Posted: 2017-07-10

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
Last Updated: 2020-02-19
Originally Posted: 2017-07-25

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)
Last Updated: 2020-02-19
Originally Posted: 2018-05-15

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)
Last Updated: 2020-02-18
Originally Posted: 2017-07-06

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)
Last Updated: 2020-02-18
Originally Posted: 2017-07-10

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
Last Updated: 2020-02-17
Originally Posted: 2017-05-15

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors
Last Updated: 2020-02-17
Originally Posted: 2018-02-09

Immune Checkpoint Inhibitor Nivolumab in People With Select Rare CNS Cancers
Last Updated: 2020-02-15
Originally Posted: 2017-05-31

A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
Last Updated: 2020-02-14
Originally Posted: 2013-06-10

Fimepinostat in Treating Brain Tumors in Children and Young Adults
Last Updated: 2020-02-10
Originally Posted: 2019-03-26

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
Last Updated: 2020-02-07
Originally Posted: 2015-02-09

Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery
Last Updated: 2020-02-07
Originally Posted: 2019-04-01

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With No Curative First-Line Treatment Option, Recurrent or Refractory Solid Tumors And Primary Cns Tumors, With or Without Trk, Ros1, or Alk Fusions
Last Updated: 2020-02-04
Originally Posted: 2016-01-04

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
Last Updated: 2020-02-03
Originally Posted: 2012-01-04

Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Last Updated: 2020-02-03
Originally Posted: 2014-03-13

DOTATOC PET/CT for Imaging NET Patients
Last Updated: 2020-01-21
Originally Posted: 2018-06-08

Dose Escalation Study of CLR 131 in Children and Adolescents With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma
Last Updated: 2020-01-20
Originally Posted: 2018-03-20

Components of Social Functioning in Survivors of Pediatric Brain Tumors
Last Updated: 2020-01-17
Originally Posted: 2017-11-28

Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma
Last Updated: 2020-01-14
Originally Posted: 2016-03-25

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors
Last Updated: 2020-01-10
Originally Posted: 2018-03-21

StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord
Last Updated: 2019-12-27
Originally Posted: 2019-06-17

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors
Last Updated: 2019-12-02
Originally Posted: 2019-11-26

HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors
Last Updated: 2019-11-20
Originally Posted: 2016-04-27

Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors
Last Updated: 2019-11-05
Originally Posted: 2012-07-30

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children
Last Updated: 2019-10-24
Originally Posted: 2017-02-02

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG
Last Updated: 2019-10-17
Originally Posted: 2019-08-02

Study of the Bromodomain (BRD) and Extra-Terminal Domain (BET) Inhibitor BMS-986158 in Pediatric Cancer
Last Updated: 2019-10-12
Originally Posted: 2019-04-30

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors
Last Updated: 2019-10-11
Originally Posted: 2019-07-11

EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors
Last Updated: 2019-10-04
Originally Posted: 2018-08-15

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors
Last Updated: 2019-09-23
Originally Posted: 2017-12-05

Study of Stored Tumor Samples in Young Patients With Brain Tumors
Last Updated: 2019-09-20
Originally Posted: 2009-05-09

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors
Last Updated: 2019-09-12
Originally Posted: 2019-04-09

68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.
Last Updated: 2019-09-11
Originally Posted: 2019-09-04

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors
Last Updated: 2019-09-05
Originally Posted: 2015-12-27

Metronomic and Targeted Anti-angiogenesis Therapy for Children With Recurrent/Progressive Medulloblastoma
Last Updated: 2019-08-24
Originally Posted: 2011-05-17

Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT
Last Updated: 2019-08-20
Originally Posted: 2016-11-02

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children With Recurrent Posterior Fossa Brain Tumors
Last Updated: 2019-06-21
Originally Posted: 2016-09-07

Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC)
Last Updated: 2019-06-19
Originally Posted: 2017-09-01

Methionine PET/CT Studies In Patients With Cancer
Last Updated: 2019-06-17
Originally Posted: 2009-02-09

Rare CNS Tumors Outcomes &Risk
Last Updated: 2019-06-12
Originally Posted: 2017-08-15

A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors
Last Updated: 2019-02-18
Originally Posted: 2018-11-05

Study of Tomotherapy HD in Medulloblastoma
Last Updated: 2018-09-16
Originally Posted: 2018-09-16

Interest of a Dose Decrease for Radiotherapy Associated With Chemotherapy for Treatment of Standard Risk Adult Medulloblastomas
Last Updated: 2018-07-03
Originally Posted: 2013-05-16

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer
Last Updated: 2018-04-13
Originally Posted: 2004-08-04

International HIT-MED Registry (I-HIT-MED)
Last Updated: 2017-10-17
Originally Posted: 2015-02-04

International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma
Last Updated: 2017-05-05
Originally Posted: 2014-02-07

Study of Sequential High-dose Chemotherapy in Children With High Risk Medulloblastoma
Last Updated: 2016-06-08
Originally Posted: 2013-12-30